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Evolution of Biopharming
1990
2001
2006
2012
2015
2014
2015
Scott Deeter CEO of Ventria Biosciences
Human serum albumin, is serum albumin found in human blood. The most abundant protein is found in blood plasma, thus it was made from tobacco and potato plants
ProdiGene, a privately owned biotech, was the first to make transgenic plant. A protein called trypsin produced in corn kernels and sold to the pharmaceutical industry. A year later they were shutdown by USDA due to contamination of plants.
Dow AgroSciences for Newcastle created a vaccine for a poultry disease from tobacco plants that was approved in the US. It was also the world's first licensed injection of plant made vaccine
Elelyso, by Protalix BioTherapeutics/Pfizer, is the first plant cell-based enzyme replacement therapy approved by the FDA. Manufactured in carrot cells, the drug is used to treat Gaucher disease.
Zmapp is created by tobacco plants to cure Ebola. Zmapp was created by Mapp Biopharmaceutical, Inc., based in San Diego
Kentucky Bioprocessing LLC, receives approval for field of tobacco. Tobacco expresses bovine lung aprotinin. Aprotinin is a trypsin inhibitor used to stem bleeding during surgeries.
Ventria Biosciences receives approval for a field of rice that engineered pharmaceutical proteins that included lactoferrin which control immune responses in infants. As well as food additive, lysozyme, serum albumin, and transferrin, iron binding protein.
2018
Dance Biopharm Holdings Inc. develops soft mist inhalable formulations of biologics. They have developed phase I/IIa as a portable hand held mist insulin inhaler for people with diabetes.
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